First listed on: 06 November 2020

CSIRO Postdoctoral Fellowship in Medicinal Chemistry for Fragment-Based Drug Discovery 

The Opportunity
  • Do you have, or will you shortly obtain, a PhD in synthetic organic or medicinal chemistry?
  • Use your organic chemistry knowledge to develop new molecules with antiviral activity
  • Join CSIRO and kick-start your research career!

CSIRO Early Research Career (CERC) Postdoctoral Fellowships provide opportunities to scientists and engineers who have completed their doctorate and have less than three years of relevant postdoctoral work experience. These fellowships aim to develop the next generation of future leaders of the innovation system.

In this position, you will undertake research to develop new molecules with antiviral activity using fragment-based approaches directed at novel drug targets. While your focus will be on synthetic organic chemistry, you will join a team of scientists in the Biomedical Manufacturing Program undertaking a range of research including structural biology, biophysics, molecular cell biology and virology. 

Your duties will include:
  • Carrying out innovative, impactful research of strategic importance to CSIRO that will, where possible, lead to novel and important scientific outcomes.
  • Assisting with directing fragment-based approaches against viral protein targets identified by other team members.
  • Using rational drug design skills and in consultation with the team, proposing new synthetic targets to translate fragment hits into potent and selective small molecule binders.
  • Planning and performing synthetic organic chemistry experiments to generate novel compounds.

Location: Melbourne (Clayton) VIC
Salary: AU$86k - AU$94k plus up to 15.4% superannuation
Tenure: Specified term of 3 years
Reference: 70113

To be considered you will need:
  • A doctorate (or will shortly satisfy the requirements of a PhD) in a relevant discipline area such as medicinal chemistry and/or synthetic organic chemistry. Please note: To be eligible for this role you must have no more than 3 years (or part-time equivalent) of postdoctoral research experience.
  • Demonstrated experience in synthetic organic chemistry techniques and planning routes to novel compounds.
  • Proven experience in the isolation and characterisation of small molecules using techniques such as NMR, chromatography, MS, HPLC.
  • A history of creatively solving synthetic organic chemistry problems. 
  • High-level communication skills including the ability to present research outcomes at national and international conferences.
  • A sound publication record in peer reviewed journals and/or authorship of scientific papers, reports or patents.

For full details about this role please view the Position Description


The successful applicant will be required to obtain and provide a National Police Check or equivalent.

Flexible Working Arrangements

We work flexibly at CSIRO, offering a range of options for how, when and where you work. Talk to us about how this role could be flexible for you. Balance

Diversity and Inclusion

We are working hard to recruit diverse people and ensure that all our people feel supported to do their best work and feel empowered to let their ideas flourish. Diversity and Inclusion Strategy

We are committed to the safety and wellbeing of all children and young people.


At CSIRO, Australia's national science agency, we solve the greatest challenges through innovative science and technology.

Join us and start creating tomorrow today!

How to Apply

Please apply on-line and provide a cover letter and CV that best demonstrate your motivation and ability to meet the requirements of this role.

Applications Close

22nd November 2020, 11:00pm AEDT

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