The Australian Medical Association (AMA) says it is worried about an apparent spike in vancomycin resistant enterococcus (VRE) infections at the Royal Hobart Hospital.

There have been 26 cases reported in the last three month compared with just two for the same quarter last year.

“It's significant because it can lead to major problems with infection that is difficult to treat in people who are immuno-compromised, or who have catheters in dwelling, or who are in hospital for a prolonged period of time,” AMA state president Tim Greenaway said.

“Whilst healthy people can live with the organism without difficulty, it can be spread by hospital workers, healthcare workers, from one individual to another, and in hospital where patients are immuno-suppressed or vulnerable; it's a very significant issue.”

Dr Greenaway said the dangerous bug can easily be spread by hospital workers.

“All hospital staff have been reminded of the importance of hand hygiene and careful control of the infectious disease precautions, and screening patients when they come out of critical care,” he said.

Royal Hobart Hospital acting chief executive Adrianne Belchamber said the hospital was aware of the issue.

“VRE is a bacteria that is not uncommon in hospitals and aged care facilities,” she said.

“We are working with the infection control unit to manage and reduce the presence of the bacteria by following standard precautionary procedures.

“Actions include screening, infection control for all patients and enhanced environmental cleaning.”

Information has been provided to patients, families and staff.